The Heart-Brain Connection: The Key to Personalised rTMS Treatment

Psychiatry is increasingly moving toward stratified and personalised intervention. Connectivity between the cortex and the limbic system is one of the strongest predictors of rTMS response. However, this connectivity profile varies between individuals.

Several rTMS targets demonstrate therapeutic efficacy, and most clinics simply select one of those locations. Yet evidence supports multiple viable targets- and not all are equally effective for every patient.

At NAYA Health, we apply a heart–brain coupling approach to guide precision neuromodulation.

By measuring heart rate deceleration across four evidence-based stimulation sites, we identify the location that most effectively engages the individual’s regulatory brain network. Target selection is therefore informed by measurable autonomic response rather than protocol convention.

This enables genuinely personalised rTMS treatment, grounded in physiological data.