Articles

SPR GEN

SB SBGrid · SBGrid Community News

Drugging the Undruggable

Dhirendra Simanshu

Jun 30, 2026 · 8 min read · 0 claps #sbgrid #structural-biology #pancreatic-cancer

SCI LIF GEN

SB SBGrid · SBGrid Community News

Kicking Arsenic to the Curb

This publication highlight is part of the SBGrid Communities Project focused on science education and demonstrating how structural biology…

Jun 29, 2026 · 3 min read · 0 claps #sbgrid #structural-biology #toxins

BIO LIF GEN SCI

SB SBGrid · SBGrid Community News

Could Treatment Inform Prevention? bNAB-Based Vaccines For People Living with HIV

This publication highlight is part of the SBGrid Communities Project focused on science education and demonstrating how structural biology…

Jun 29, 2026 · 2 min read · 0 claps #sbgrid #structural-biology #hiv

LIF GEN SCI

SB SBGrid · SBGrid Community News

Uncovering a Lung-to-Brain Pathway for Nicotine-Induced Neural Stress

This publication highlight is part of the SBGrid Communities Project focused on science education and demonstrating how structural biology…

May 28, 2026 · 2 min read · 0 claps #sbgrid #structural-biology #smoking

LIF GEN SCI

SB SBGrid · SBGrid Community News

Not Too Cold, Just Right!

This publication highlight is part of the SBGrid Communities Project focused on science education and demonstrating how structural biology…

May 28, 2026 · 3 min read · 0 claps #sbgrid #structural-biology #temperature

SPR

SB SBGrid · SBGrid Community News

How proteins work together to support our vision

SBGrid member Antonia Roll-Mecak analyzes the structure of the RPGR-TTLL5 complex to understand the pathomechanism of retititis pigmentosa.

Apr 29, 2026 · 2 min read · 0 claps #sbgrid #structural-biology #cytoskeleton

BIO MDA SCI GEN

SB SBGrid · SBGrid Community News

Molecular Proofreading: Mechanisms of Enzyme Binding

SBGrid member Jochen Zimmer describes the two-step mechanism CvHAS uses to navigate the balance between substrate specificity and…

Apr 28, 2026 · 3 min read · 0 claps #cryoem #degeneracy #binding

TCH BIO GEN

SB SBGrid · SBGrid Community News

Structure-guided Antibiotics

Andrés Palencia of National Institute of Health and Medical Reserves works to develop drugs to combat drug-resistant bacteria and…

Mar 29, 2026 · 7 min read · 0 claps #sbgrid #structural-biology #tuberculosis

BIO HUM GEN

SB SBGrid · SBGrid Community News

Electric Bacteria: Biological “Power Cords”

SBGrid member Fengbin (Jerry) Wang of University describes their use of CryoEM to identify the biological “power cords” bacteria use.

Feb 26, 2026 · 2 min read · 0 claps #sbgrid #structural-biology #cryoem

SB SBGrid · SBGrid Community News

How signals move through the brain

SBGrid member Edward Twomey characterizes structural features of the AMPA-subtype glutamate receptor GluA4 subunit.

Feb 26, 2026 · 3 min read · 0 claps #sbgrid #structural-biology #ampar

MED SCI GEN SPR

SB SBGrid · SBGrid Community News

Promising small molecule may help with sudden cardiac death

SBGrid Member Chuck Sanders reports on a small molecule that may change the trajectory of LQTS intervention research.

Jan 29, 2026 · 3 min read · 1 claps #sbgrid #structural-biology #lqt

LIF SOC BIO GEN

SB SBGrid · SBGrid Community News

The Stories Antibodies Tell

Jean-Philippe Julien from The Hospital for Sick Children interrogate antibodies that arise from natural infections and vaccine trials.

Jan 28, 2026 · 7 min read · 0 claps #sbgrid #structural-biology #malaria

BIO GEN

SB SBGrid · SBGrid Community News

Mapping bacteriophages

SBGrid member Mihnea Bostina helps to uncover the first high-resolution, head-to-tail structural map of a Felixounavirus bacteriophage.

Nov 30, 2025 · 2 min read · 50 claps #sbgrid #structural-biology #bacteriophages

BIO GEN

SB SBGrid · SBGrid Community News

Getting rid of arsenic

SBGrid member William Clemons Jr. looks at how the ArsA enzyme reshapes itself to capture and expel toxic arsenic.

Sep 28, 2025 · 2 min read · 0 claps #sbgrid #structural-biology #atpase

GEN

SB SBGrid · SBGrid Community News

Understanding how positive allosteric modulators regulate metabotropic glutamate receptors

SBGrid member Joshua Levitz and colleagues examine how PAMs improve the function and internalization of mGluRs.

Aug 27, 2024 · 3 min read · 0 claps #sbgrid #structural-biology #mglur

GEN

SB SBGrid · SBGrid Community News

New insights into how antibodies regulate GPCR signaling

SBGrid member Andew Kruse from Harvard Medical School, explores the use of engineered antibodies, called nanobodies, to enhance targeting…

May 30, 2024 · 2 min read · 1 claps #sbgrid #structural-biology #gpcr

SCI

SB SBGrid · SBGrid Community News

The movement of T cells

SBGrid member Timothy Springer and other researchers have been working to better understand how actin polymerization plays a role in…

Nov 26, 2016 · 1 min read · 0 claps #sbgrid #structural-biology #actin

SPR

SB SBGrid · SBGrid Community News

Hidden in the muscle: The structure of myosin

SBGrid member Ivan Rayment and other researchers worked to elucidate the structure of the myosin rod by dividing it into smaller protein…

Dec 07, 2015 · 1 min read · 0 claps #sbgrid #structural-biology #myosin