Author

MedChemExpress

@medchemexpress_llc

articles: 23
total claps: 1,983
top claps: 201
avg read: 5.4 min
active: 2025-07-03 → 2026-09-11

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PHM · Pharmacology & Drug Discovery · 12 ONC · Oncology · 9 MIC · Microbiology & Immunology · 6 🔬 · Science · General · 6 BIO · Biology · General · 4 🧠 · Mental Wellness · 3 BCH · Biochemistry · 2 BTC · Biotechnology · 2

Top tags

#drug-discovery ·12 #cancer ·7 #biomedical ·4 #cells ·3 #health ·3 #life-sciences ·3 #organoid ·2 #immune-system ·2 #neurodegenerative-disease ·2 #drug-delivery ·2

BIO GEN MED SCI

ME MedChemExpress

Revolutionizing Cancer Treatment: Targeting DNA Damage Repair Pathways to Overcome Resistance

Cancer treatment is often hindered by the emergence of drug resistance. Traditional anticancer therapies primarily exert their effects by…

Feb 25, 2026 · 8 min read · 201 claps #dna #drug-discovery #dna-damage

Revolutionizing Cancer Treatment: Targeting DNA Damage Repair Pathways to Overcome Resistance

MED

ME MedChemExpress

Engineered Exosomes: An Emerging Platform for Therapeutic Drug Delivery

Exosomes are nanoscale extracellular vesicles secreted by cells. They have recently emerged as promising drug delivery vehicles. These…

Feb 12, 2026 · 4 min read · 198 claps #exosome #drug-delivery #drug-discovery

BIO GEN MDA MED

ME MedChemExpress

Why Mitochondria Matter in Cellular Senescence and Aging

How mitochondrial quality control, metabolism, and innate immunity shape cellular fate

Sep 11, 2026 · 13 min read · 197 claps #cells #mitochondria #biomedical

Why Mitochondria Matter in Cellular Senescence and Aging

BIO SPT MED SPR SCI

ME MedChemExpress

Cracking the Code of Pyroptosis: A Guide to Its Mechanisms and Detection

Pyroptosis is a lytic and inflammatory form of programmed cell death (PCD). It is characterized by cell swelling, membrane perforation, and…

Feb 04, 2026 · 7 min read · 190 claps #pyroptosis #life-sciences #cell-death

Cracking the Code of Pyroptosis: A Guide to Its Mechanisms and Detection

GEN MDA BIO MED

ME MedChemExpress

Nucleic Acid Drug Delivery Systems: Advances and Future Perspectives

Nucleic acid drugs (NADs) have emerged as a promising approach for treating genetic diseases, cancer, viral infections, and other complex…

Feb 12, 2026 · 8 min read · 188 claps #nucleic-acids #drugs #drug-delivery

Nucleic Acid Drug Delivery Systems: Advances and Future Perspectives

BIO SCI MED

ME MedChemExpress

Cracking the PROTAC Permeability Barrier: CD36-Mediated Endocytosis as a Potential Breakthrough

I Background: PROTACs — great potential, real challenges

Jan 23, 2026 · 5 min read · 184 claps #drug-discovery #protac #life-sciences

Cracking the PROTAC Permeability Barrier: CD36-Mediated Endocytosis as a Potential Breakthrough

BIO SCI

ME MedChemExpress

Macrophages 101: Roles, Types, and How Scientists Study Them

A Comprehensive Guide to Macrophage Differentiation, Polarization, and Identification

Jan 22, 2026 · 6 min read · 167 claps #macrophage #immunology #cell-biology

Macrophages 101: Roles, Types, and How Scientists Study Them

BIO MED SCI

ME MedChemExpress

Cancer in 2026: Scientific Breakthroughs Are Growing, but the Global Cancer Gap Remains

The world is making progress against cancer — but not everyone is benefiting equally.

Jul 30, 2026 · 3 min read · 138 claps #cancer #drug-discovery #oncology

Cancer in 2026: Scientific Breakthroughs Are Growing, but the Global Cancer Gap Remains

BIO HUM TCH MED

ME MedChemExpress

Organoid Advances in Cancer Research & Drug Discovery

Organoids are three-dimensional (3D) miniature structures cultured in vitro produced from either human pluripotent stem cells (hPSCs) or…

Apr 03, 2026 · 4 min read · 137 claps #organoid #cancer #drug-discovery

Organoid Advances in Cancer Research & Drug Discovery

SOC MED GEN

ME MedChemExpress

Next-Gen Parkinson’s Research: Exploring Targets, Disease Models, and Biomarker Breakthroughs

Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disease that leads to severe disability and imposes an increasing…

Apr 08, 2026 · 9 min read · 111 claps #parkinson-disease #disease-model #drug-discovery

Next-Gen Parkinson’s Research: Exploring Targets, Disease Models, and Biomarker Breakthroughs

BIO MED TCH GEN LIF SCI

ME MedChemExpress

Gene Therapies for Heart Failure Are Making a Comeback — Can the Field Finally Deliver?

For years, gene therapy for cardiovascular disease was viewed as one of biotechnology’s biggest disappointments.

Jun 02, 2026 · 3 min read · 99 claps #health #science #heart-disease

Gene Therapies for Heart Failure Are Making a Comeback — Can the Field Finally Deliver?

LIF MED

ME MedChemExpress

GLP-1 Isn’t Just About Weight Loss: What Happens When We Block It?

If you’ve been following the latest developments in obesity and diabetes, you’ve probably heard a lot about GLP-1.

Sep 08, 2026 · 3 min read · 90 claps #glp-1 #obesity #diabetes

GLP-1 Isn’t Just About Weight Loss: What Happens When We Block It?

MDA HUM MED

ME MedChemExpress

HLA-E, A Novel Immune Checkpoint

Big news in tumor immunity! A new immune checkpoint, HLA-E, has been discovered in circulating tumor cells (CTCs). How can you miss this!

Jul 21, 2025 · 6 min read · 50 claps #checkpoints #ctla-4 #circulating-tumour-cells

ME MedChemExpress

Peptides in the Pathogenesis Alzheimer’s Disease

Alzheimer’s Disease (AD) is one of the most common forms of neurodegenerative disease characterized by progressive cognitive decline. The…

Jul 03, 2025 · 1 min read · 16 claps #alzheimer-disease #peptides #β-amyloid-fragments

Peptides in the Pathogenesis Alzheimer’s Disease

GEN LIF BIO MED

ME MedChemExpress

Harnessing the immune system to turn cold tumors hot

Cold Tumors vs Hot Tumors

Apr 22, 2026 · 2 min read · 15 claps #tumor #cancer #car-t-cell-therapy

Harnessing the immune system to turn cold tumors hot

HUM BIO MED

ME MedChemExpress

Tumor Organoid-Immune Cell Co-Culture Models: Advances, Applications, and Future Directions

Tumor organoids, as three-dimensional (3D) in vitro culture models, have emerged as powerful tools in cancer research and drug screening…

May 09, 2026 · 7 min read · 1 claps #immune-system #cancer #cancer-research

Tumor Organoid-Immune Cell Co-Culture Models: Advances, Applications, and Future Directions

ME MedChemExpress

Mechanistic Insights into Anti-Infective Pathways: Current and Future Therapeutics

Overview of Anti-infection Signaling Pathway

Jul 30, 2025 · 1 min read · 1 claps #infection #infectious-disease #anti-infectives

Mechanistic Insights into Anti-Infective Pathways: Current and Future Therapeutics

MED SPT GEN LIF

ME MedChemExpress

From Casgevy to Base Editing: Rare Disease Therapy Enters the Programmable Medicine Era

Over the past decade, genome editing has evolved from a research technology into a clinically validated therapeutic platform, with the…

Jul 03, 2026 · 13 min read · 0 claps #gene-editing #drug-discovery #rare-disease

From Casgevy to Base Editing: Rare Disease Therapy Enters the Programmable Medicine Era

ECO MDA MED

ME MedChemExpress

The Dual Role of Cellular Senescence in Cancer: Mechanisms, Microenvironment, and Therapeutics

Cellular senescence, originally defined as an irreversible cell-cycle arrest program, suppresses tumorigenesis by limiting the…

May 15, 2026 · 10 min read · 0 claps #cancer #tumor #senescence

The Dual Role of Cellular Senescence in Cancer: Mechanisms, Microenvironment, and Therapeutics

MED

ME MedChemExpress

BBO-11818: An Orally Bioavailable Pan-KRAS Inhibitor for KRAS-related Cancer Research

KRAS is a major oncogenic driver in multiple cancers, with clinically relevant mutations including KRASG12D, KRASG12V, and KRASG12C…

Aug 31, 2026 · 3 min read · 0 claps #cancer #drug-discovery #inhibitor

BBO-11818: An Orally Bioavailable Pan-KRAS Inhibitor for KRAS-related Cancer Research

BIO MED

ME MedChemExpress

A Closer Look at Bundibugyo Ebola Virus Disease

Bundibugyo Ebola virus disease (BVD) is a rare but severe form of Ebola virus disease caused by the Bundibugyo ebolavirus, a member of the…

May 22, 2026 · 2 min read · 0 claps #public-health #virus #ebola

A Closer Look at Bundibugyo Ebola Virus Disease

ECO

ME MedChemExpress

Unlocking the Power of Covalent Drug Design

Covalent drugs have accounted for about 30% of the drugs on the market.

Jul 25, 2025 · 2 min read · 0 claps #drugs #covalentalchemist #unruggable

Unlocking the Power of Covalent Drug Design

BIO SPT MED

ME MedChemExpress

Nb-PROTAC Enables a Broad-Spectrum Breakthrough Against Influenza A

Influenza A viruses remain a persistent global health challenge, driven by rapid mutation and the frequent emergence of drug resistance…

May 22, 2026 · 1 min read · 0 claps #nature #protac-technology #influenza