Articles

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DN DNAnexus · DNAnexus Science Frontiers

Infrastructure Challenges: Machine Learning in the Cloud as a Future Oriented Solution using UK…

Ondrej Klempir, Ph.D., Sr. Community Engagement Scientist, DNAnexus & Ben Busby, PhD, Principal Scientist, DNAnexus

Jun 30, 2023 · 6 min read · 3 claps #machine-learning #bioinformatics #biobanking

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DN DNAnexus · DNAnexus Science Frontiers

A New Twist on Diagnostics Development: Partnership with SynBio Pioneers to Accelerate NGS-based…

Methylation and low-frequency variation detection made easier? By combining our integrated, comprehensive computational platform with…

Jul 13, 2022 · 2 min read · 1 claps #bioinformatics #life-sciences #genomics

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DN DNAnexus · DNAnexus Science Frontiers

New Paper Highlights Results from Recent PrecisionFDA Truth Challenge

Scientists from DNAnexus, the Genome In a Bottle consortium, and other institutions have published a paper in Cell Genomics that shares…

Jun 21, 2022 · 2 min read · 54 claps #bioinformatics #precision-medicine #fda

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AR Arkarachai (Chai) Fungtammasan, PhD · DNAnexus Science Frontiers

How to Perform Large-scale Data Processing in Bioinformatics

A Complementary Discussion for “Ten Simple Rules for Large-scale Data Processing”

Apr 18, 2022 · 8 min read · 120 claps #biotechnology #big-data #bioinformatics

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YI Yih-Chii Hwang, Ph.D. · DNAnexus Science Frontiers

An exploration of machine-learning based variant callers for SNV and small-indel using PacBio HiFi…

Prepared by: Yih-Chii Hwang, PhD, Arkarachai Fungtammasan, PhD, and Jason Chin, PhD

Dec 16, 2021 · 9 min read · 125 claps #long-read-sequencing #machine-learning #genomics

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CH Chiao-Feng Lin · DNAnexus Science Frontiers

Predicting Adverse Drug Reactions with Drug-Specific Cohorts

By Vikrant Magadi

Nov 10, 2021 · 6 min read · 4 claps #adverse-drug-reactions #uk-biobank-rap #lightgbm

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JA Janka Puterova · DNAnexus Science Frontiers

Single-cell sequencing on DNAnexus: Smart-Seq2 pipeline

Migrating the publicly available Smart-Seq2 multi-sample workflow written in WDL from the Broad Institute’s WARP to the DNAnexus Platform

Oct 12, 2021 · 8 min read · 1 claps #bioinformatics #single-cell-sequencing #workflow-automation

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YI Yih-Chii Hwang, Ph.D. · DNAnexus Science Frontiers

Perform genome-wide association analysis to identify exome variants in Alzheimer's disease in UK…

Prepared by: Yih-Chii Hwang, PhD, Ames Ma and Jason Chin, PhD

Sep 01, 2021 · 6 min read · 100 claps #uk-biobank #researchanalysisplatform #gwas

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CH Chiao-Feng Lin · DNAnexus Science Frontiers

Are you susceptible to adverse drug reactions?

Prediction and insights using LightGBM and SHAP — Part two

Feb 16, 2021 · 5 min read · 9 claps #pharmacogenomics #adverse-drug-reactions #uk-biobank

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CH Chiao-Feng Lin · DNAnexus Science Frontiers

Are you susceptible to adverse drug reactions?

Prediction and insights using LightGBM and SHAP — Part one

Feb 16, 2021 · 5 min read · 9 claps #pharmacogenomics #adverse-drug-reactions #uk-biobank

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AR Arkarachai (Chai) Fungtammasan, PhD · DNAnexus Science Frontiers

Towards a Truly “Personalized” Genome Part 2:

De novo assembly and haplotype phasing of diploid human genomes using long High-fidelity reads and non-trio phasing approaches

Jan 12, 2021 · 7 min read · 45 claps #genome-assembly #personalized-medicine #phasing

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AR Arkarachai (Chai) Fungtammasan, PhD · DNAnexus Science Frontiers

Towards a Truly “Personalized” Genome

Part 1: De novo assembly and haplotype phasing diploid of human genome using noisy ultra-long read and trio-binning approach

Jun 10, 2020 · 8 min read · 18 claps #genome-assembly #phasing #long-read-sequencing