Proteomics & Structure

AI LIF GEN

DR DrSwarnenduAI · Data And Beyond

AI Is Rewriting the Code of Life.

A baby named KJ was born with a genetic typo.

May 14, 2026 · 14 min read · 321 claps paywalled #gene-therapies #alphafold #google

BIO ECO TCH GEN

GA Gabriel Papelheim

Revolution in Protein Structure Prediction: AlphaFold 2 and RoseTTaFold Released as Open-Source…

One of the most challenging problems in molecular biology is determining the folded form of a protein’s long chain. The 3D structure of the…

Jan 16, 2023 · 2 min read · 201 claps #alphafold #protein #rosettafold

AI GEN

HS HSD TRU · HUAWEI Student Developers Turkiye

Yapay Zekâ Biyolojiyi Nasıl Çözüyor? AlphaFold ve Protein Katlanması Üzerine

Bilim insanlarının 50 yıldır boğuştuğu problem, bir yapay zekâ tarafından nasıl çözüldü?

May 19, 2026 · 4 min read · 200 claps #yapay-zeka #alphafold #protein-katlanması

AI BIO GEN

CO Colby T. Ford, Ph.D.

Am I Hallucinating or Can AI Now Design Cancer-Curing Antibodies?

AlphaFold2 Hallucinated to make a new Cancer Antibody

Jun 08, 2022 · 3 min read · 145 claps #antibody-design #alphafold #dalle-2

AI HUM TCH GEN

HA Hayanan · Data Science Collective

The Alien Within: Decoding Why Artificial Intelligence Operates on Logic No Human Mind Has Ever…

Fro⁠m Al‍phaGo’‌s Move 3​7 to​ spontaneous n‍umber t⁠heory, mechanistic superposition,​ and phase-transition emergence the accumulatin​g…

Jun 16, 2026 · 26 min read · 110 claps paywalled #artificial-intelligence #deep-learning #alphafold

AI BIO MED GEN

DR DrSwarnenduAI · Data And Beyond

Biochemists Spent 50 Years Failing to Solve This Problem.

In November 2020, a competition judge watched a computer predict protein structures with an accuracy that took his breath away. He said…

May 22, 2026 · 12 min read · 109 claps paywalled #ai #biology #drug-discovery

AI GEN

SU Sushila Devi

The Nobel Winner Who Walked Away

The remarkable story of John Jumper, AlphaFold, and why one of the world’s brightest scientists chose a new path.

Jun 20, 2026 · 3 min read · 100 claps paywalled #nobel-prize #john-jumper #alphafold

AI BIO HUM LIF GEN

IM Immanuel Sanka

If I were focusing on protein modeling back then…

I might be stumbled into different world of AI nowadays.

Dec 08, 2025 · 8 min read · 92 claps #ai #alphafold #bioinformatics

BIO SCI DSN GEN

CP C. Price Jones

A practical guide to RNA scaffold cryoEM

Goal: Here I explain how to design, use, and analyze my version of RNA scaffolds created to expedite RNA structure determination. This…

Mar 19, 2026 · 18 min read · 76 claps #rna #science #structural-biology

GEN LIF

SC 𝐆𝐫𝐫𝐥𝐒𝐜𝐢𝐞𝐧𝐭𝐢𝐬𝐭, scientist & journalist

The Old Irish Goat Carries 3,000 Years Of Irish History In Its DNA

Goats tell us how human values changed through time by showing how and where we moved animals through trade or migration.

May 22, 2026 · 5 min read · 74 claps paywalled #ireland #proteomics #genomics

ECO GEN

SA Satish Kothapalli

How Drug Design Works, Why It Takes So Long, and How AI Like AlphaFold3 Speeds It Up

Imagine a world where a new medicine could be created much quicker, saving millions of lives. That’s the dream — and it’s getting closer…

Mar 03, 2025 · 5 min read · 57 claps #drug-design #drug-designing-tools #alphafold-3

BIO GEN SCI

HA Harvard Undergraduate Microbiology Society

The Long Awaited Pursuit of Scientists: Cryo-EM

With a more specific understanding of pathogens’ behavior, scientists can also create solutions that target their exact behaviors.

Dec 02, 2025 · 3 min read · 54 claps #science #microbiology #bacteria

DSN AI BIO HUM TCH GEN SCI

MA Marco Lolaico · Plenty of Room

AI-Designed Protein Hitting: Taming Disordered Protein Structure!

Read here for free.

May 17, 2026 · 4 min read · 54 claps paywalled #ai #science #biotech

SCI GEN

RA Raisul Awal Mahmood

Mass Spectrometry Part 1 — Fundamentals

Basic principle of mass spectrometry:

Oct 03, 2025 · 2 min read · 52 claps #mass-spectrometry #chemical-analysis #chemical-compounds

ART GEN

DR Drraghavendra · CodeToDeploy

The Molecular Architecture of Life: An End-to-End Computational Journey Through Proteomics…

Introduction: From Reductionism to Holistic Living Systems

Jun 24, 2026 · 11 min read · 50 claps #proteomics #metabolomics #pharmacogenomics

BIO GEN

SB SBGrid · SBGrid Community News

Mapping bacteriophages

SBGrid member Mihnea Bostina helps to uncover the first high-resolution, head-to-tail structural map of a Felixounavirus bacteriophage.

Nov 30, 2025 · 2 min read · 50 claps #sbgrid #structural-biology #bacteriophages

AI BIO GEN SCI

LU LucianoSphere (Luciano Abriata, PhD) · Advances in biological science

From zero to foundation, look at this great introductory article on protein structure prediction…

Here recommending someone else’s piece, which serves as a superb introduction to AlphaFold, Protein Language Models, and more

May 01, 2026 · 5 min read · 44 claps paywalled #bioinformatics #science #data-science

BIO SPT ECO GEN

KU Kushal Shah

From AlphaFold to ESM3: The Era of Programmable Biology

The biological world is governed by the Central Dogma: a 1D amino acid sequence dictates a complex 3D structure, which ultimately defines a…

Jun 09, 2026 · 7 min read · 40 claps #large-language-models #evolutionary-biology #computational-biology

AI BIO SCI HUM MED GEN

LU LucianoSphere (Luciano Abriata, PhD) · Advances in biological science

State of the Art of Protein Structure Prediction as of 2025, as Evaluated by CASP16

Advancements in modeling complexes involving proteins, nucleic acids, small molecules ligands, and more

Mar 26, 2025 · 4 min read · 39 claps paywalled #bioinformatics #artificial-intelligence #science

AI BIO GEN SCI

LU LucianoSphere (Luciano Abriata, PhD) · Advances in biological science

Two upcoming “AlphaFold moments”: design of protein binders and prediction of conformational states

And brainstorming a future of super-multimodal foundational AI models for biology.

May 08, 2026 · 11 min read · 37 claps paywalled #science #technology #biology